tissue
Lung Immune Ecosystem
Air-exposed barrier where epithelial alarmins, macrophage tone, and type 2 circuits regulate airway reactivity
Review layer
Last reviewed 2026-05-17
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
State signature
Systems profile
Tissue ecosystem
Spatial immune niche
niche
Lung
Barrier
Cells
Cytokines
Neuroimmune
Graph neighborhood
Direct relationships
Airway-resident mast cells shape bronchial reactivity
Allergic airway type 2 loops
Airway epithelial injury and alarmin release
Mucus, airway reactivity, and tissue remodeling
Airway resident immune memory shapes recall, tolerance, and remodeling after inhaled exposures
Immune niche
Tissue Ecology
The lung balances inhaled antigen tolerance, antiviral readiness, allergic repair programs, and neutrophilic injury risk.