IMMUNE OSby Allerim

reference

IgG

Systemic memory antibody family for opsonization, neutralization, complement, Fc receptor signaling, and placental transfer

immunoglobulinmemoryopsonizationFc receptor

Review layer

Last reviewed 2026-05-17

conceptualeducational

Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.

antibody

Systems Context

IgG is not one behavior; subclass, antigen specificity, Fc receptor context, and Fc glycan state decide the immune-state effect.

Clinical Use

Total IgG, subclasses, and vaccine responses should be interpreted together in recurrent infection or immune deficiency workups.

Aliases

Expressed By

Memory B cellsLong-lived plasma cells

Targets

protein antigenspolysaccharide antigensFcγ receptorsC1qFcRn

Functions

neutralizationopsonizationADCCcomplement activationlong-lived humoral memory