reference
C1q / classical complement
Antibody-triggered complement entry point connecting immune complexes to opsonization and inflammation
complementIgGIgMopsonization
Review layer
Last reviewed 2026-05-17
conceptualeducational
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
pathway
Systems Context
Complement turns antibody binding into a tissue-level clearance and inflammation program.
Clinical Use
Frames immune-complex disease, antibody effector function, recurrent infection, and complement-mediated inflammation.
Aliases
Expressed By
Complement systemMacrophagesLiver-derived plasma proteins
Targets
IgM complexesIgG complexesapoptotic materialpathogens