IMMUNE OSby Allerim

reference

FcRn

Neonatal Fc receptor that recycles IgG and albumin and supports long antibody half-life

IgGFc receptorhalf-lifeplacenta

Review layer

Last reviewed 2026-05-17

conceptualeducational

Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.

receptor

Systems Context

FcRn is the persistence layer of the IgG system; it determines how long systemic antibody information remains available.

Clinical Use

Important for therapeutic antibody pharmacology, maternal-fetal immunity, and IgG persistence logic.

Aliases

Expressed By

EndotheliumEpitheliumAntigen-presenting cellsPlacenta

Targets

IgGalbumin

Functions

IgG recyclinghalf-life extensionplacental transfermucosal transport