IMMUNE OSby Allerim

reference

Short-chain fatty acids

Microbial metabolites that support tolerance, barrier health, and regulatory immune tone

microbiomeTregtolerancegut

Review layer

Last reviewed 2026-05-17

conceptualeducational

Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.

metabolite

Systems Context

SCFAs are a metabolic language of microbial resilience.

Clinical Use

Frames how microbiome disruption can reduce tolerance and permit TH17 or allergic drift.

Aliases

SCFAsbutyrateacetatepropionate

Expressed By

Microbiome

Targets

Tregsepitheliummacrophagesdendritic cells

Functions

Treg supportbarrier energyHDAC modulationresolution tone