tissue
Mucosal Lymphoid Ecosystem
Tonsils, adenoids, Peyer's patches, and MALT as antigen-sampling hubs for IgA, tolerance, allergy, and barrier memory
Review layer
Last reviewed 2026-05-17
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
State signature
Systems profile
System effects
Primary mapped axes from existing Atlas data.
Tissue
Organ, barrier, stromal, vascular, or local niche behavior.
Tolerance
Immune restraint, resolution, regulatory tone, or set-point control.
Chronicity
Memory, priming, fibrosis, exhaustion, remodeling, or other time-dependent drift.
Tissue ecosystem
Spatial immune niche
niche
Mucosal Lymphoid Ecosystem
Barrier
Cells
Cytokines
Neuroimmune
Graph neighborhood
Direct relationships
Arrow shows upstream source toward receiving target.
MALT supports IgA class switching, mucosal memory, and antigen-specific barrier defense
Arrow shows upstream source toward receiving target.
Tfh-B cell collaboration in mucosal follicles shapes local antibody quality and tolerance
Context link: no causal arrow.
Mucosal lymphoid tissues organize antigen sampling, TH17 instruction, IgA context, and barrier memory
Immune niche
Tissue Ecology
Mucosal lymphoid tissues translate inhaled, swallowed, microbial, and food antigens into IgA responses, tolerance programs, Tfh/B-cell collaboration, and barrier-local immune memory.