reference
KIT / CD117
Stem cell factor receptor supporting mast cell development, survival, and tissue residency
mast cellSCFsurvivaltissue residency
Review layer
Last reviewed 2026-05-17
conceptualeducational
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
surface-marker
Systems Context
KIT is less about acute activation and more about whether the tissue can maintain a mast-cell-rich niche.
Clinical Use
Useful in mast cell identification and disorders involving mast cell burden or KIT mutations.
Aliases
Expressed By
Mast CellMast Cell Progenitor
Targets
Stem cell factor