pathway
Extracellular Vesicle Networks
Immune cell communication through vesicle cargo, tissue stress packets, and inflammatory propagation.
Review layer
Last reviewed 2026-05-17
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
future
Systems Frame
Extracellular vesicles move proteins, lipids, RNA, and stress information between cells, making them a future layer for graph-based immune state modeling.
Core Concepts
Key Interactions
Inflamed tissue can export vesicle cargo that primes distant immune sites.
Tumors use vesicle signaling to remodel immune surveillance.
Barrier stress vesicles may contribute to systemic inflammatory patterning.
Scenario Examples
tumor EVs -> immune suppression
endothelial EVs -> thromboinflammation
microglial EVs -> neuroimmune propagation