pathway
Autonomic & HRV Physiology
Vagal tone, sympathetic load, HRV, recovery state, inflammatory reflexes, and neuroimmune threshold control.
Review layer
Last reviewed 2026-05-17
Systems teaching draft. Content is structured for education and graph expansion, with formal source tagging ready for the next review pass.
core
Systems Frame
This module connects autonomic balance to immune thresholds, vascular tone, mast cell sensitivity, macrophage restraint, and recovery trajectories.
Core Concepts
Key Interactions
Low recovery state can raise inflammatory set point and symptom sensitivity.
Vagal signaling can restrain macrophage cytokine output.
Sympathetic and sensory signals can lower mast cell thresholds in barrier tissues.
Scenario Examples
low HRV -> inflammatory priming
stress load -> mast cell sensitization
sleep recovery -> improved tolerance tone